The series deals with the scenario of the transformation of a man into a woman with spells, which were made by a disappointed girlfriend of his, Romina. So Leonidas Lalos a successful man, director at the men's magazine Mister, the ultimate male who had the reputation of being a heart conqueror among women, mutated into a beautiful woman. The series focuses on Leonidas Lalo, who now takes the name Lola Lalou and appears supposedly as Leonidas' cousin, trying to keep his job and his old life. However, on the one hand, she is constantly in search of a solution to the problem of mutation, and on the other, in the unexpected aspect of a new life, as she now falls in love with her colleague, Fotis Stergiou.